Rickettsia typhi


RICKETTSIA TYPHI

The Murine typhus (from Latin mus ,  or endemic typhus , is a form of exanthematic typhus transmitted by fleas of rats. Mouse typhus is caused by the bacterium Rickettsia typhi and develops in tropical and subtropical areas. In tropical countries it is often confused with dengue. It is transmitted through the rat flea (hence the Murine name), the Xenopsylla cheopis , or more rarely through the flea Ctenocephalides felis , than parasitic cats and opossum.

Symptoms include, among others: headache, fever (for periods of more than 2 weeks), chills, joint pain, nausea, vomiting and cough, abdominal pain, back pain. Precise diagnosis is possible through a serological test, and a complete blood test which may reveal anemia and low platelet levels, with lower albumin and sodium levels. The pathology is normally treated with the use of antibiotics such as Doxycycline, Tetracycline and Chloramphenicol. If not properly treated, this disease leads to death ranging from 10% to 60% of cases, with an increase in death probabilities in patients over the age of 60. The disease is present in some regions such as the Canary Islands, Texas and Japan. In 2011 a case was found in Naples.

Sensitivity

Specificity

Positive Control



& nbsp;

Negative Control

& nbsp;

93%

& nbsp;

98%

& nbsp;

mixture of antigen Dilution 1

& nbsp;

93%

& nbsp;

98%

& nbsp;

mixture of antigen Dilution 2

& nbsp;

93%

& nbsp;

98%

& nbsp;

mixture of antigen Dilution 3

& nbsp;

93%

& nbsp;

98%

& nbsp;

mixture of antigen Dilution 4





Total reaction time: 40 minutes at 44-47 ° C.

First incubation: 15 minutes

Second incubation: 5 minutes

Third incubation: 15 minutes

First incubation: 5 minutes

Ref: 110-0428 25 tests