Leptospira biflexa


LEPTOSPIRA BIFLEXA

The leptospirosis (also known as field fever, seven days fever, autumn fever, fever fever or pretibial fever) is a vascular systemic acute vascular disease caused by spirochete of Leptospira . Symptoms may vary from mild as headache, muscle aches and severe fever with hemorrhage from the lungs or meningitis. If the infection is accompanied by jaundice, kidney failure and haemorrhage, the condition is called Weil’s disease, by its discoverer, and the disease may be deadly (40-50% of cases ).

There are ten different types of leptospira that cause diseases in humans. They are transmitted from domestic and wild animals, including the most common rodents (especially rats), but also dogs, cattle, pigs, birds and reptiles. Infection is often transmitted by animal urine or water that it contains and comes into contact with abrasions or cuts on the skin, or in the eyes, mouth, nose or vagina. Diagnosis is done through the culture of bacteria from a blood sample, with the search for bacterial DNA in the blood or the search for antibodies against infection. It is estimated that between 7 and 10 million people worldwide contract leptospirosis every year. In most cases, the infection begins in an entirely unavoidable way. Therapy is antibiotic: doxycycline, ampicillin, amoxicillin, penicillin, ceftriaxone or cefotaxime are regularly used to eradicate the disease.

Sensitivity

Specificity

Positive Control



Dilution 1

67-91%

94%

Dilution 2

67-91%

94%

Dilution 3

67-91%

94%

Dilution 4

67-91%

96%

Negative Control





Total reaction time: 40 minutes at 44-47 ° C.

First incubation: 15 minutes

Second incubation: 5 minutes

Third incubation: 15 minutes

First incubation: 5 minutes

Ref: 700-0553 25 tests