AMH, anti-muellerian hormone

In mammals it is secreted by the Sertoli’s cells of the fetal testis during early stages of development. it is responsible in the male fetus of the Müllerian ducts regression, embryonic structures at the origins of the uterus, Fallopian tubes and the top of the vagina .

Although measurable in males during childhood and adulthood, AMH can not be found in females until puberty when it is produced by the granule ovary cells to control the formation of primary follicles by inhibiting excess follicular stimulation from part of the FSH.

AMH is measured on serum. In women, AMH levels are unmeasurable during the menopause and after removal of the ovaries, and almost indigestible at birth. They grow after puberty, then stabilize in adulthood, then begin to decrease as a function of the reduction in ovarian reserve. This shows that AMH comes from the ovary.