EBV VCA Panel IgG


EBV VCA Panel IgG

 

EBV or Type 4 Human Herpes Virus was isolated in London for the first time in 1964 by Anthony Epstein and Yvonne Barr. By isolating a cellular line and analyzing cells in the electronic microscope, Epstein and Barr discovered the presence of this new herpesvirus, which in their honor was called Epstein-Barr (EBV) virus.

Since 1968, it has been known that in most infected individuals EBV does not cause pathological manifestations or cause an indistinguishable form from common respiratory infections from viruses; in some cases it is responsible for benign disease known as infectious mononucleosis and in any case it is associated, in addition to Burkitt’s lymphoma, to other types of malignant tumors, including Hodgkin’s lymphoma and breastfeeding carcinoma, common in South East Asia and the Maghreb.

Virus transmission occurs mainly with saliva. (segue)

Sensitivity

Specificity
Positive control
 

EBV-VCA (lysated part. purified P3HR1 strain)

 

99.6%

 

93%

 

EBNA-1 (baculovirus, purified, type B95-8) 1

 

98.7%

 

89%

 

CMV (lysate of strain glycine AD-169)

 

100%

 

100%

 

Toxoplasma gondii: purified membrane fractions

 

100%

 

100%

 

Negative control

 

 

Total reaction time: 100/140 minutes at 44-47 ° C.

First incubation: 60/90 minutes

Second incubation: 5 minutes

Third incubation: 30/40 minutes

First incubation: 5 minutes

 

Ref: 800-6015 25 tests