EBV VCA Panel IgG |
EBV or Type 4 Human Herpes Virus was isolated in London for the first time in 1964 by Anthony Epstein and Yvonne Barr. By isolating a cellular line and analyzing cells in the electronic microscope, Epstein and Barr discovered the presence of this new herpesvirus, which in their honor was called Epstein-Barr (EBV) virus.
Since 1968, it has been known that in most infected individuals EBV does not cause pathological manifestations or cause an indistinguishable form from common respiratory infections from viruses; in some cases it is responsible for benign disease known as infectious mononucleosis strong> and in any case it is associated, in addition to Burkitt’s lymphoma, to other types of malignant tumors, including Hodgkin’s lymphoma and breastfeeding carcinoma, common in South East Asia and the Maghreb.
Virus transmission occurs mainly with saliva. (segue)
Sensitivity td> | Specificity td> | |
Positive control | ||
EBV-VCA (lysated part. purified P3HR1 strain) |
99.6% |
93% |
EBNA-1 (baculovirus, purified, type B95-8) 1 |
98.7% |
89% |
CMV (lysate of strain glycine AD-169) |
100% |
100% |
Toxoplasma gondii: purified membrane fractions |
100% |
100% |
Negative control |
Total reaction time: 100/140 minutes at 44-47 ° C.
First incubation: 60/90 minutes
Second incubation: 5 minutes
Third incubation: 30/40 minutes
First incubation: 5 minutes
Ref: 800-6015 25 tests